Gluten Sensitivity: New Epidemic or New Myth?

Gluten sensitivity: new epidemic or new myth?

Fueled in part by recent bestselling books that warn of the evils of gluten in our diets, a significant proportion of our population is now either avoiding foods that contain gluten or eliminating gluten entirely from their diets, and these numbers continue to grow. The gluten-free trend-and the accompanying multibillion-dollar industry it has created-stems from the spreading belief that eating...

Celiac or non-celiac gluten sensitivity. The new debate.

New immunofluorescent blood test for gluten sensitivity.

A new test for the detection of antibodies to gliadin in the sera of children who are gluten sensitive is described. This test is based on the observation that wheat protein binds selectively to connective tissue fibres in cryostat sections of mammalian tissues. Sera containing antibodies to gliadin give a reticulin pattern of staining on section pretreated with wheat gliadin if tested by indir...

Exploring the Strange New World of Non-Celiac Gluten Sensitivity.

This month’s issue of Clinical Gastroenterology and Hepatology features the latest clinical trial investigating the phenomenon of non-celiac gluten sensitivity (NCGS). Although NCGS has been reported for at least 35 years, clinical trials to rigorously investigate this syndrome are still in their infancy. To date, only a few prospective randomized clinical trials on the role of gluten in induci...

Non-Celiac Gluten Sensitivity: The New Frontier of Gluten Related Disorders

Non Celiac Gluten sensitivity (NCGS) was originally described in the 1980s and recently a "re-discovered" disorder characterized by intestinal and extra-intestinal symptoms related to the ingestion of gluten-containing food, in subjects that are not affected with either celiac disease (CD) or wheat allergy (WA). Although NCGS frequency is still unclear, epidemiological data have been generated ...